SVMDECON {ADAPTS} | R Documentation |
Use SVMDECONV to estimate the cell count percentage David L Gibbs, dgibbs@systemsbiology.org June 9, 2017
v-SVR is applied with a linear kernel to solve for f, and the best result from three values of v = 0.25, 0.5, 0.75 is saved, where ‘best’ is defined as the lowest root mean squared error between m and the deconvolution result, f x B.
Our current implementation executes v-SVR using the ‘svm’ function in the R package, ‘e1071’.
w2 <- SVMDECON(m, B)
SVMDECON(m, B)
m |
a matrix represenging the mixture (genes X 1 sample) |
B |
a matrix representing the references (genes X cells), m should be subset to match B |
A matrix with cell type estimates for each samples